Application Prospects of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9) in Kidney Diseases
Abstract：This article introduces the current popular gene editing technology - clustered regularly interspaced short palindromic repeats (CRISPR/Cas9) and its potential applications in the field of kidney diseases. It discusses how this technology can correct genetic defects causing kidney diseases, analyzes its possibilities in regulating metabolic disorders, improving renal fibrosis, alleviating inflammation, and kidney transplantation. At the same time, it discusses the challenges faced by this technology, including off-target effects, ethical issues, and difficulties in clinical translation.
Keywords：Gene EditingNephrologyClustered Regularly Interspaced Short Palindromic RepeatsReview
Publication Date：2025-09-15
Online Publishing Date：2025-10-31(First online date of this platform, not the publication date of the document)
Pages：6( 45-50 )