DOI: 10.1002/ame2.70068
Research progress on traditional Chinese medicine animal models of post-stroke depression and pathological insights
Jielin Wang1
Wenlu Ma1
Wei Wu2
Yujuan Fu1
Hui Li2
1.School of Basic Medical Science,Changchun University of Chinese Medicine,Changchun,P.R.China2.Jilin Ginseng Academy,Changchun University of Chinese Medicine,Changchun,P.R.China
摘要：Post-stroke depression(PSD)is a common psychiatric complication affecting nearly one-third of stroke survivors,leading to increased disability,mortality,and cogni-tive decline.Traditional Chinese Medicine(TCM)has proven effective in treating PSD through syndrome differentiation,yet existing animal models primarily reflect Western medical concepts and fail to incorporate the TCM principle of "同病异治"(treating the same disease with different methods).This paper provides a review of the current methods for constructing animal models of post-stroke depression(PSD)from the perspective of Traditional Chinese Medicine(TCM)syndrome differentiation and proposes multi-dimensional assessment indicators.By integrating TCM theories with modern biomedical techniques,this study offers a comprehensive framework for deepening the understanding of the pathogenesis and therapeutic evaluation of PSD.This approach not only contributes to advancing PSD research but also paves the way for innovative treatment strategies that combine traditional and modern medicine.
机标关键词：depressioninsightsmedicinechineseresearchmodelsanimalpathological
论文发表日期：2025-08-30
在线出版日期：2025-11-05（本平台首次上网日期，不代表文献的发表时间）
页数：13( 1387-1399 )
英文信息