DOI: 10.1002/ame2.70109
Radiation emergency medical countermeasures:Current formulary,identified gaps,and future approaches
Wen-Bing Ma1
Rong-Hua Yin2
Guang-Ming Ren2
Yin Zhang1
Li-Juan Li1
Wei Liu1
Ting Chen1
Wei Zhou1
Mian Zu1
Rong-Ling Yin1
Xin-Di Shi1
Lei Wang1
Xiao-Ming Yang2
1.Academy of Military Medical Sciences,Beijing,China2.State Key Laboratory of Medical Proteomics,Beijing
摘要：Radiological or nuclear accidents can lead to serious outcomes for individuals exposed to ionizing radiation,with health effects that are either acute or delayed,deterministic or stochastic,depending on the effective dose of exposure.Mechanistically,ionizing radiation can inflict damage either directly on DNA or through oxidative stress,which may trigger a cascade of damages to tissues and organs.The development of effec-tive radiation medical countermeasures is an unmet need and should be a top priority in preparing for radiation emergencies.This paper aims to address the critical ques-tions of whether current countermeasures are available,what additional measures are needed,and what actions can be taken to enhance the development of radiation medical countermeasures from a systematic perspective.
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论文发表日期：2025-11-30
在线出版日期：2026-01-09（本平台首次上网日期，不代表文献的发表时间）
页数：14( 2008-2021 )
英文信息