DOI: 10.1002/ame2.70126
Animal models of benign airway stenosis:Advances in construction techniques,evaluation systems,and perspectives
Wusheng Zhang
Yilin Chen
Chengcheng Yang
Yuchao Dong
Haidong Huang
Hui Shi
Chong Bai
Department of Respiratory and Critical Care Medicine,The First Affiliated Hospital of Naval Medical University,Shanghai,China
摘要：The incidence of benign airway stenosis(BAS)is on the rise,and current treatment options are associated with a significant risk of restenosis.Therefore,there is an urgent need to explore new and effective prevention and treatment methods.Animal models serve as essential tools for investigating disease mechanisms and assessing novel therapeutic strategies,and the scientific rigor of their construction and valida-tion significantly impacts the reliability of research findings.This paper systematically reviews the research progress and evaluation systems of BAS animal models over the past decade,aiming to provide a robust foundation for the optimized construction of BAS models,intervention studies,and clinical translation.This effort is intended to fa-cilitate the innovation and advancement in BAS prevention and treatment strategies.
机标关键词：evaluationsystemsmodelsadvancesairwayanimalbenignconstruction
论文发表日期：2026-02-28
在线出版日期：2026-03-31（本平台首次上网日期，不代表文献的发表时间）
页数：18( 280-297 )
英文信息