Anal intraepithelial neoplasia diagnosis and treatment advanc-es
Yifan Wang
Huadong Tang
Qing Liu
Department of Gynecology,Beijing Youan Hospital,Capital Medical University,Beijing,China
摘要：Human papillomavirus(HPV)infection can lead to the development of anal intraepithelial neoplasia(AIN)and anal cancer.The incidence of anal cancer is increasing each year,with the risk varying widely among different populations.The currently identified significant risk factors for anal cancer include men who have sex with men,human immunodeficiency virus carriers,a history of genital warts and non-anal genital HPV infection,immu-nosuppression,and smoking.Studies have shown that screening and treatment of AIN in these populations can help prevent anal cancer.Anal cancer screening refers to the three-step model of cervical cancer screening,which includes the use of cytology,anal HPV testing,identification of high-grade lesions by high-resolution anoscopy in patients with positive screening results,and the removal of lesions by ablation,surgical excision,or other ther-apies.The biology of AIN remains poorly understood and prospective data are limited.The current recommenda-tions for AIN screening and treatment are based on expert opinion and require the support of additional medical evidence from future studies.
机标关键词：advanc-esanaldiagnosisintraepithelialneoplasiatreatment
论文发表日期：2024-09-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：12( 40-51 )
英文信息