Epstein–Barr virus-associated gastric cancer:pathogenesis,molecular characterization,and emerging therapies
Yiqian Wang1
Dachuan Zhang2
Yue Zhang1
Meihua Wang3
Qing Li2
1.Department of Pathology,The Third Affiliated Hospital of Soochow University(Changzhou First People's Hospital),Changzhou 213004,Jiangsu,China;Department of Pathology,Changzhou Cancer Hospital,Changzhou 213032,Jiangsu,China2.Department of Pathology,The Third Affiliated Hospital of Soochow University(Changzhou First People's Hospital),Changzhou 213004,Jiangsu,China3.Department of Pathology,Changzhou Cancer Hospital,Changzhou 213032,Jiangsu,China
摘要：Gastric cancer is the fifth most common malignant tumor in the world in terms of morbidity and mortality,with a high prevalence of gastric cancer in Asia,especially in China,Japan,and South Korea.Gastric cancer is strong-ly associated with Epstein–Barr virus,and gastric cancer cases positive for Epstein–Barr virus are referred to as Epstein–Barr virus-associated gastric cancer(EBVaGC).EBVaGC has unique clinicopathological features and molecular characteristics,and the study of EBVaGC provides new perspectives for the early diagnosis and person-alized treatment of gastric cancer.Here,we present a review of the research progress in the epidemiology,patho-genesis,clinicopathologic features and prognosis,molecular features,diagnosis,and treatment of EBVaGC.
机标关键词：molecularcancervirustionassociatedbarrcharacteremerging
论文发表日期：2024-12-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：10( 23-32 )
英文信息