Progress and challenges in the clinical cure of children with chronic hepatitis B on antiviral treatment
Peiyao Fan1
Jing Li2
Fusheng Wang2
1.Department of Infectious Diseases,The Fifth Medical Center of Chinese PLA General Hospital,National Clinical Research Center for Infectious Diseases,Beijing 100039,China;Peking University 302 Clinical Medical School,Beijing 100191,China2.Department of Infectious Diseases,The Fifth Medical Center of Chinese PLA General Hospital,National Clinical Research Center for Infectious Diseases,Beijing 100039,China
摘要：Recent advancements in the prevention and management of chronic hepatitis B virus(HBV)infection in children have significantly improved clinical outcomes.This review focuses on recent progress in antiviral treatment reg-imens for children with HBeAg-positive chronic hepatitis B in the immune clearance phase and HBeAg-positive HBV infection in the immune tolerance phase.Additionally,we examine the role of early antiviral intervention in infants with acute or chronic HBV infection,highlighting factors that influence the likelihood of achieving clinical cure in children with chronic HBV.We further discuss the importance of timely decision-making in initiating anti-viral therapy for pediatric patients and identify unresolved challenges and unmet needs in this evolving field.
机标关键词：childrenclinicalcurewithantiviralchallengeschronichepatitis
论文发表日期：2025-03-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：9( 2-9,47 )
英文信息