Changes in hepatic blood flow after splenectomy and pericar-dial devascularization
Xiaofei Zhao1
Zizhao Zhu2
Pu He3
Liang Di1
Guangming Li1
Daobing Zeng1
1.Department of General Surgery Center,Beijing You'an Hospital,Capital Medical University,Beijing 100069,China2.Department of General Surgery(First Division),Shenyang Sixth People's Hospital,Shenyang,China3.Department of Thoracoabdominal Surgery,Shijiazhuang Sixth Hospital,Shijiazhuang,China
摘要：Objective To analyze hemodynamic changes in the portal vein and hepatic artery after splenectomy and pericar-dial devascularization.
Methods A total of 132 patients with portal hypertension who underwent splenectomy and pericardial devascu-larization in Beijing You'an Hospital from June 2014 to June 2017 were selected.Hemodynamic changes in the portal vein,hepatic artery,and hepatic elasticity were recorded before and at 1,3,6,12,24,and 36 months after the operation,and the characteristics of hepatic blood flow before and after surgery were analyzed.
Results Among the 132 patients,there were 89 men and 43 women aged 27-74 years,with a mean±standard deviation)age of 48.6±10.6 years.Liver stiffness at 1,3,6,12,24,and 36 months after surgery was significantly lower than that preoperatively(all P<0.05).Additionally,portal vein flow and velocity at 1,3,6,12,and 24 months after surgery were sig-nificantly lower than those preoperatively(all P<0.05).Liver stiffness was positively correlated with portal vein flow and velocity.Hepatic artery flow at 1 month after surgery was significantly higher than that preoperatively(P<0.05).
Conclusions After splenectomy and pericardial devascularization,short-term and long-term liver stiffness,portal vein flow,and mean velocity are lower than those preoperatively.Liver stiffness is positively correlated with portal vein flow and mean velocity.Splenectomy and pericardial devascularization may partially reverse liver cirrhosis and improve liver function.
机标关键词：bloodafterflowchangeshepaticpericar-dialsplenectomyvascularization
论文发表日期：2025-09-30
在线出版日期：2025-12-02（本平台首次上网日期，不代表文献的发表时间）
页数：6( 46-51 )
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