Advances in the detection methods for assessing the viability of cryopreserved samples
Yan Hao1
Zhicheng Liu2
Heming Sun3
Wang Zhai2
Wenyu Sun2
Long Mu4
1.Shandong Yinfeng Life Science Research Institute,Jinan 250102,China2.Yinfeng Cryomedicine Technology Co.,Ltd.,Jinan 250102,China3.University of Florida,Department of Computer and Information Science and Engineering,Florida 32611,United States4.Department of Neurosurgery,The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital,Jinan 250014,China
摘要：Since the beginning of the 21st century,modern medical technology has advanced rapidly,and the cryomedicine has also seen significant progress.Notable developments include the application of cryomedicine in assisted reproduction and the cryopreservation of sperm,eggs and embryos,as well as the preservation of skin,fingers,and other isolated tissues.However,cryopreservation of large and complex tissues or organs remains highly challenging.In addition to the damage caused by the freezing and rewarming processes and the inherent complexity of tissues and organs,there is an urgent need to address issues related to damage detection and the investigation of injury mechanisms.It provides a retrospective analysis of existing methods for assessing tissue and organ viability.Although current techniques can detect damage to some extent,they tend to be relatively simple,time-consuming,and limited in their ability to provide timely and comprehensive assessments of viability.By summarizing and evaluating these approaches,our study aims to contribute to the improvement of viability detection methods and to promote further development in this critical area.
机标关键词：detectionadvancesassessingcryopreservedmethodssamplesviability
论文发表日期：2025-06-30
在线出版日期：2025-09-23（本平台首次上网日期，不代表文献的发表时间）
页数：6( 113-118 )
英文信息