Correlation between bladder compliance and the content of detrusor collagen fibers
Hai-Yan Zhang
Hai-Xu Ji
Wei Li
Jin-Hua Zhang
摘要：Objective: To explore the possible correlation between bladder compliance (BC) and the changes in detrusor collagen fiber content after bladder outlet obstruction (BOO). Methods: Ninety healthy female Sprague-Dawley (SD) rats were enrolled in this experiment and divided into an experimental group and a control group randomly, using the randomizing table method, with 70 rats in the experimental group and 20 rats in the control group. Six weeks after BOO modeling was established, BC was evaluated through bladder testing. Bladder tissues were then fixed and embedded in paraffin. The tissues were cut into thin slices, followed by Masson staining and observation under a microscope. Results: Compared with the control group, the BC of the experimental group rats increased, and the difference had statistical significance (P<0.05);the content of detrusor collagen fibers of the rats in the experimental group increased significantly compared to the control group. Conclusions: The content of detrusor collagen fibers increased significantly after BOO, and BC was higher.
机标关键词：collagen fibersbladder outlet obstructionstatistical significance
论文发表日期：2016-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：3( 83-85 )
英文信息