The Different Patterns of Coronary Artery Calcification in Acute and Chronic Coronary Syndromes Determined by Electron Beam Computed Tomography
杜志民
罗初凡
胡承恒
李怡
伍贵富
李向民
冯君
唐安丽
马虹
1.Department of Cardiology, First Affiliated Hospital of Sun Yat - sen University of Medical Sciences, Guangzhou 510080, P R China2.Department of Cardiology, First Affiliated Hospital of Sun Yat - sen University of Medical Sciences, Guangzhou 510080, P R China3.Department of Cardiology, First Affiliated Hospital of Sun Yat - sen University of Medical Sciences, Guangzhou 510080, P R China4.Department of Cardiology, First Affiliated Hospital of Sun Yat - sen University of Medical Sciences, Guangzhou 510080, P R China5.Department of Cardiology, First Affiliated Hospital of Sun Yat - sen University of Medical Sciences, Guangzhou 510080, P R China6.Department of Cardiology, First Affiliated Hospital of Sun Yat - sen University of Medical Sciences, Guangzhou 510080, P R China7.Department of Cardiology, First Affiliated Hospital of Sun Yat - sen University of Medical Sciences, Guangzhou 510080, P R China8.Department of Cardiology, First Affiliated Hospital of Sun Yat - sen University of Medical Sciences, Guangzhou 510080, P R China9.Department of Cardiology, First Affiliated Hospital of Sun Yat - sen University of Medical Sciences, Guangzhou 510080, P R China
摘要：Objectives To compare thedifferent patterns of coronary artery calcification (CAC)in acute and chronic coronary syndromes utilizingelectron beam computed tomography. BackgroundPathologic, angiographic, and intracoronary ultrasoundstudies revealed sharp differences in the plaque mor-phology between patients with acute versus chroniccoronary syndromes. Whether there are different pat-terns of coronary artery calcification in patients withstable angina pectoris (SAP) and in those with unstableangina pectoris (UAP) or acute myocardial infarction(AMI), however, remains unclear. Methods Twohundred and sixty- four patients, including 67 withSAP, 94 with UAP and 103 with AMI were studied withelectron beam computed tomography for analysis ofcoronary artery calcification and with selective coronaryangiography for determination of atherosclerotic le-sions. CAC prevalence and calcium score were com-pared among three groups, and relation of CAC to theseverity of atherosclerotic disease in the SAP and UAPpatients was separately analyzed. Results Preva-lence of CAC was 100 % in the SAP patients, signifi-cantly higher than the 87.23 % in UAP patients and86.41% among the patients with AMI ( P ＜ 0.05) .More patients and arteries in the SAP group had severeforms of calcium than those in the UAP and AMI group(P ＜0.01), and the mean LN [CS+1 | (naturallogarithm transformation of calcium score) of the SAPpatients was much greater than that of the UAP andAMI patients ( P ＜ 0. 001 ). The distribution of vesselswith various CAC by luminal stenosis was different be-tween SAP and UAP patients. The average CAC extentof the infarct - related arteries was less severe than thatof the noninfarct - related arteries. Conclusions U-tilizing electron beam computed tomography, wedemonstrated that there exist different patterns of coro-nary artery calcification in patients with acute versuschronic coronary syndromes, which may provide insightinto the differences observed in the clinical and patho-logic development between these two types of coronaryartery disease.
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分类号：R54(心脏、血管（循环系）疾病)
论文发表日期：2002-07-02
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：10( 63-71,76 )
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