Plasma Hemoglobin Was Decreased in Elderly With Primary Hypertension and/or Type 2 Diabetes Complicated With End-stage Renal Disease

Gang LI; Ling-jun GONG; Can-jing ZHANG; Yang MU; Bing-bao ZHU

摘要：Objectives To study the change in plasma hemoglobin concentration in elderly patients with primary hypertension and/or type 2 diabetes complicated with end-stage renal disease(ESRD) determined by estimated glomerular filtration rate. Methods Two hundred and thirty cases of Chinese patients aged 60 years or older with primary hypertension and/or type 2 diabetes complicated with chronic kidney disease were enrolled in the study. Patients with chronic kidney(7.80±3.14mL·min-1·1.73m-2) and non-ESRD group with estimated glomerular filtration rate 15mL·min-1·1.73m-2(29.76±12.90mL·min-1·1.73m-2)or higher. The plasma hemoglobin concentration was compered between the above two groups retrospectively. Results There was significant decrease in plasma hemoglobin concen-tration in ESRD group compared with non-ESRD group(74. 4 ± 22. 5 g/L vs 100. 8 ± 23.0 g/L, P < 0. 05). After stratification by sex, there was also significant decrease in plasma hemoglobin concentration both in male and female of ESRD groups compared with their respective non-ESRD groups(77.2 ± 22. 0 g/L vs 104. 9 ± 20. 7 g/L; 69. 7 ± 22. 8 g/L vs 96. 4 ± 24. 8 g/L, P < 0. 05, respectively). Plasma hemoglobin concentration was positively related to esti-mated glomerular filtration rate significantly in patients with ESRD (P < 0. 05). Condusions Plasma hemoglobin con-centration is decreased significandy, and is positively related to estimated glomerular filtration rate significantly in elder-ly patients with primary hypertension and/or type 2 diabetes complicated with ESRD determined by estimated glomeru-lar filtration rate.