Research progress of the relationship between angiotensinogen gene polymorphisms and coronary heart disease
WANG Yu-Jing
PAN Yan
摘要：Coronary heart disease(CHD)is a major health problem in many countries and its pathogenesis is not yet fully understood,contributing to significant morbidity and mortality.Accumulated evidence manifest clearly that CHD is determined by a complex interplay of genetic and environmental factors.Many clinical data have showed that the renin-angiotensin system(RAS)involved in many cardiovascular diseases,such as hypertension and CHD.Angiotensinogen(AGT)is the key components of the RAS system,and two gene polymorphisms of AGT had been detected of the CHD risk:M235T and T174M. This article reviews the effects of ACT gene polymorphisms on the CHD.
机标关键词：
分类号：R541.4(心脏、血管（循环系）疾病)
论文发表日期：2011-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
英文信息