The effects and mechanisms of thyroid hormones in the cardiovascular system
ZHANG Yan-chun1
ZHANG Jin-guo2
1.Jining Medical University, Jining 271067, Shandong2.Department of Cardiology, the Affiliated Hospital of Jining Medical University, Jining 272029, Shandong, China
摘要：Background Thyroid hormones (THs) including thyroxine (T4) and triiodothyronine (T3) with high biological activities have important effects on cardiovascular system by acting on renin-angiotensin-aldosterone system (RAAS),oxidative stress,mitochondria,endothelial cells,vascular smooth muscle cells (VSMC),cardiomyocytes,thyroid hormone receptor (TRs),cholesterol metabolism,insulin sensitivity,blood coagulation,etc.Excess or lack of THs is detrimental to cardiovascular function,so this article reviews the mechanism of THs on cardiovascular system.
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论文发表日期：2019-12-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：11( 269-279 )
英文信息