Prevalence of congenital heart disease among live birth in Hainan,China
ZHANG Du-fei1
CHEN Ren-wei2
MO Ze-lai3
YANG Ling4
WANG Ya-zhou1
WANG Hai-fan2
1.Cardiovascular Department,Hainan Women and Children's Medical Center,Haikou 570000,China2.Cardiac Surgery Department,Hainan Women and Children's Medical Center,Haikou 570000,China3.Ultrasound Department,Hain-an Women and Children's Medical Center,Haikou 570000,Chi-na4.Neonatal Department,Hainan Women and Children's Medical Center,Haikou 570000,China
摘要：Background The prevalence and risk factors of congenital heart disease in Hainan is currently unknown.Methods This study enrolled 117005 consecutive neonates born at delivery institutions of 17 urban and rural re-gions in Hainan from January 1,2020 to December 31,2020.Cases of CHD were identified by pulse oximetry(POX) combined with auscultation screening,echocardiography,and follow-up.Results A total of 572 new-borns (50.7％ males) were diagnosed with CHD,providing an overall CHD prevalence of 4.89 per 1000 live births in Hainan,and the prevalence of insignificant,significant,serious and critical CHD was 2.13,2.25,0.28 and 0.23 per 1000 live births,respectively.The most common congenital heart lesion was atrial septal defect(ASD),at a prevalence of 1.889 per 1000.Compared with those without CHD,the proportion of preterm births was obviously higher among the newborns with CHD,especially the newborns with significant and critical CHD.Compared with those without CHD,The proportion of low birthweight infants was obviously higher among the newborns with CHD (serious and critical).In comparison to the Chinese Han population,some other ethnic groups (Miao,Hani and Mi) showed an obviously higher prevalence of CHD.Correlation analysis showed that the prevalence of CHD was positively correlated with altitude (r=0.513,P=0.035).Conclusions Pulse oximetry(POX) combined with auscultation is suitable for CHD screening in remote areas.Premature birth,low birth weight and the rise of altitude were risk factors for CHD.This study obtained accurate data on the prevalence and risk factors of CHD in Hainan,which provided the epidemiological information of CHD in Hainan,China.
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论文发表日期：2021-12-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 256-262,278 )
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