Triglyceride-glucose index predicts the prognosis of patients with acute myocardial infarction
LUN Zi-heng
HE Jie-xin
FU Ming
YI Shi-xin
ZHANG Ying
Department of Cardiovascular Medicine,Guangdong Cardiovas-cular Institute,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510180,Guangdong,China
摘要：Background Research has indicated that the triglyceride-glucose(TyG)index is associated with the develop-ment and prognosis of cardiovascular diseases.However,there is still uncertainty regarding whether the TyG index can predict adverse cardiovascular events in patients with acute myocardial infarction(AMI).The present study aimed to explore the prognostic value of the TyG index in patients with AMI.Methods AMI patients who under-went emergency percutaneous coronary intervention(PCI)in Guangdong General Hospital from February 2021 to June 2022 were enrolled.The study population was grouped based on the median TyG index.The end point of the study was major adverse cardiovascular events(MACEs),defined as all-cause mortality,cardiogenic shock,recur-rent myocardial infarction,acute attack of heart failure,repeat revascularization induced by cardiac ischemia,and urgent visit due to aggravation of chest pain.The TyG index was calculated as follows:LN[fasting triglycerides(mg/dL)× fasting blood glucose(mg/dL)xl/2].Results A total of 196 patients were included.In the multivariate logistic regression analysis,TyG index[odds ratio(OR):0.99,95％confidence interval(CI):0.45-2.16,P=0.98]was not significantly correlated with the occurrence of MACEs in AMI patients during hospitalization.Afterwards a total of 178 patients were followed up for an average of 12.66±5.35 months.In the multivariate Cox proportional hazards model,TyG index[hazard ratio(HR):1.91,95％CI:1.02-3.6,P＜0.05]were independent predictor of ad-verse events during follow-up,and the area under the receiver operating characteristic(ROC)curve(AUC)was 0.63(0.53-0.73,P＜0.05).Conclusions TyG index can independently predict the prognosis of AMI patients dur-ing the follow-up period.[S Chin J Cardiol 2024;25(1):11-20]
机标关键词：prognosisglucoseindexwithacuteinfarctionmyocardialpatients
论文发表日期：2024-03-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：11( 11-20,43 )
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