肌酐与射血分数比值对老年ST段抬高型心肌梗死患者短期死亡率的预测价值
LU Ping
WU YU-ting
HE YU-ying
LIAO You-wan
Department of Geriatric Intensive Care Medicine,Guangdong Provincial Geriatrics Institute,Guangdong Provin-cial People's Hospital,Guangdong Academy of Medical Scienc-es,Southern Medical University,Guangzhou 510080,China
摘要：Background Elderly patients(age≥60 years)with ST-segment elevation myocardial infarction(STEMI)are at an elevated risk of mortality.This study aimed to investigate the association of the creatinine to ejection fraction ra-tio(CER)with in-hospital and 1-year death in elderly patients with STEMI.Methods A total of 753 consecutive elderly patients(age≥60 years)with STEMI undergoing percutaneous coronary intervention(PCI)were enrolled and divided into three groups according to the tertiles of CER at admission:<1.5(n=250),1.5-2.2(n=249)and>2.2(n=254).Multivariate analyses were performed to evaluate the prognostic value of CRE for short-term death in this population.Results The in-hospital and 1-year mortality reached 6.0%and 13.3%,respectively.Patients with higher CER exhibited a higher in-hospital mortality(0.8%vs.2.8%vs.14.2%,P<0.001).An optimal cut-off value of 2.5 for CER was identified for predicting in-hospital death by receiver operating characteristic curve analysis,yielding a sensitivity of 77.8%and a specificity of 76.1%[area under curve(AUC):0.791,95%confidence interval(CI):0.734-0.847,P<0.001].Multivariate regression analyses revealed that CER>2.5 was an independent risk fac-tor for both in-hospital[adjusted odds ratio(OR):9.006,95%CI:2.707-29.967,P<0.001]and 1-year mortality[ad-justed hazard ratio(HR):5.082,95%CI:2.462-10.490,P<0.001].Conclusions Elevated CER is associated with adverse short-term mortality in elderly STEMI patients undergone PCI,offering valuable insights for the early iden-tification and management of high-risk individuals in clinical practice.[S Chin J Cardiol 2025;26(3):155-163]
机标关键词：老年st段抬高型心肌梗死心肌梗死患者射血分数死亡率预测价值短期死亡
论文发表日期：2025-09-30
在线出版日期：2025-11-03（本平台首次上网日期，不代表文献的发表时间）
页数：9( 155-163 )
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