Coarctation of the aorta in twins with severe hypertension
Guo-Hua ZHU1
Yan-Ling WANG1
Huan-Huan WANG2
Jing LI1
Jing GAO1
Hai-Ying WU1
Jun CAI2
Qi HUA1
1.Department of Cardiology, Xuanwu Hospital Capital Medical University, Beijing, China2.Department of Hypertension, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
摘要：Coarctation of the aorta (CoA) refers to the congenital coarctation near the isthmus,ductus arteriosus or ligamentum arteriosus,with an incidence of 5％-10％ in children with congenital heart defects.[1] It can be isolated or coexisted with ventricular septal defects,subaortic stenosis,patent ductus arteriosus,and mitral aortic valve.[2] CoA has a poor prognosis.Without intervention,the median age of death with aortic coarctation is 38 years[3] and 75％ death of those patients is at the age of 46 years.[4] Causes of death included congestive heart failure (26％),aortic rupture (21％),bacterial endocarditis (18％),and intracranial hemorrhage (12％).[5] Therefore,early diagnosis and optimal treatment are the key to improve the prognosis of this disease.The aim of this report is underlining the importance of early and accurate diagnose of CoA as a cause of systemic hypertension in young patients and also emphasizing the genetic factors of CoA in twins.
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论文发表日期：2019-12-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 894-897 )
英文信息