Transcatheter aortic valve replacement for older patients with isolated aortic regurgitation
José C González1
Ignacio J.Amat2
1.University Clinic Hospital of Valladolid,Spain2.University Clinic Hospital of Valladolid,Spain;Centro de Investigación biomédica en red de enfermedades cardi-ovasculares,CIBERCV,Madrid,Spain
摘要：Aortic regurgitation(AR)poses distinct challenges in interventional cardiology,necessitating novel approaches for treatment.This editorial examined the evolving landscape of transcatheter aortic valve replacement(TAVR)as an alternative therapeutic strategy for AR,particularly in patients deemed high risk for surgery.We explored the anatomical and patho-physiological disparities between AR and aortic stenosis(AS)and elucidates the technical nuances of TAVR procedures in AR pa-tients,emphasizing the need for precise prosthesis positioning and considerations for excessive stroke volume.Additionally,we discussed the safety and efficacy of TAVR compared to SAVR in AR management,drawing insights from recent case series and registry data.Notably,dedicated TAVR devices tailored for AR,such as the J-Valve and JenaValve,demonstrate promising out-comes in reducing residual AR and ensuring procedural success.Conversely,"off-label"TAVR devices,including balloon-ex-pandable and self-expandable platforms,offer feasible alternatives-particularly for large aortic annuli-with favorable device suc-cess rates and low residual AR rates.We highlighted the need for further research,including randomized trials,to delineate the definitive role of TAVR in AR treatment and to address remaining questions regarding device selection and long-term outcomes.In conclusion,TAVR emerges as a viable option for patients with AR,particularly those facing high surgical risks or frailty,with ongoing investigations poised to refine its position in the therapeutic armamentarium.
机标关键词：withaorticisolatedolderpatientsregurgitationreplacementtranscatheter
论文发表日期：2025-07-30
在线出版日期：2025-09-16（本平台首次上网日期，不代表文献的发表时间）
页数：4( 611-614 )