Outcomes in octogenarians undergoing percutaneous coro-nary intervention:nationwide data from the Netherlands Heart Registration
Nousjka PA Vranken1
Sanne Janssen2
Tobias FS Pustjens3
Romi Michon4
Lineke Derks5
Arnoud WJ van't Hof2
Saman Rasoul3
on behalf of the PCI and Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration
1.Department of Cardiology,Maastricht University Medical Centre,Maastricht,the Netherlands2.Department of Cardiology,Maastricht University Medical Centre,Maastricht,the Netherlands;Department of Car-diology,Zuyderland Medical Centre,Heerlen,the Netherlands;Cardiovascular Research Institute Maastricht(CARIM),Maastricht University,Maastricht,the Netherlands3.Department of Cardiology,Maastricht University Medical Centre,Maastricht,the Netherlands;Department of Car-diology,Zuyderland Medical Centre,Heerlen,the Netherlands4.Department of Car-diology,Zuyderland Medical Centre,Heerlen,the Netherlands5.Netherlands Heart Registration,Utrecht,the Netherlands
摘要：Background In patients with coronary artery disease,age is of known significance in predicting outcomes.Data on clinical out-comes in patients≥85 years undergoing percutaneous coronary intervention(PCI)remain scarce.The study aim was to determ-ine clinical characteristics,risk of adverse cardiovascular events,and mortality in patients aged≥85 years compared to those aged<85 undergoing PCI.
Methods In this retrospective study,data were obtained from the nationwide Netherlands Heart Registration on patients un-dergoing PCI between January 1st,2017 and January 1st,2021.The primary endpoint was all-cause mortality at long-term follow-up.
Results A total of 155,683 patients underwent PCI,of which 100,209(64.4%)acute coronary syndrome cases.Compared to pa-tients aged<85 years,patients aged≥85 were more often female and showed a higher number of cardiovascular comorbidities,including impaired left ventricle ejection fraction and reduced kidney function.Mortality at short-term and long-term follow-up were significantly higher in those aged≥85(P<0.001).Patients aged≥85 were more likely to have a myocardial infarction with-in 30 days following the index intervention(0.9%vs.0.7%;P=0.024),though they less often underwent revascularization at long-term follow-up compared to patients aged<85(P<0.001).
Conclusions The elderly(≥85 years)patient requiring PCI carries an extensive cardiovascular risk profile,translating in signi-ficant risk of recurrent cardiovascular events and increased mortality rate.Clinicians should carefully weigh perceived risks and potential benefits in the individual patient,considering the patients'age,cardiovascular risk profile,and associated risk of mor-bidity and mortality.
机标关键词：percutaneousdataheartfromcoro-naryinterventionnationwidenetherlands
论文发表日期：2026-01-30
在线出版日期：2026-03-16（本平台首次上网日期，不代表文献的发表时间）
页数：8( 1-8 )