Solid fuel use and heart disease in middle-aged and older Chi-nese populations:a prospective cohort study
Jun-Wen WANG
Ke-Xin CHEN
Teng HU
Yu-Yang YE
Yi-Fei ZHAO
Xin-Ru HU
Jiang YU
Simayi Abulikemu
Mai-Lin WEI
Jun MA
Yong PENG
Department of Cardiology,West China Hospital,Sichuan University,Chengdu,China
摘要：BACKGROUND Solid fuel use for cooking and heating is a major environmental risk factor,yet its association with new-onset heart di-sease(HD)remains unclear.The aim of this study was to investigate the relationship between solid fuel exposure and new-onset HD in a la-rge cohort.
METHODS Multivariable logistic regression models assessed associations between cooking/heating fuel types(coal,crop residue/wood,liquefied petroleum gas,natural gas,and others)and new-onset HD.Subgroup analyses explored effect modification by age,sex,edu-cation,smoking,alcohol use,and region.
RESULTS A prospective cohort study included 5915 participants,with 781 participants(13.2%)developing new-onset HD.Coal use for cooking showed an initial association with new-onset HD risk(OR=1.41,95%CI:1.06-1.86,P=0.02),which attenuated after full adjus-tment(OR=1.28,95%CI:0.96-1.72,P=0.10).Coal use for heating demonstrated robust associations across all models(OR=1.86,95%CI:1.42-2.43,P<0.001).Crop residue/wood burning for heating was also significant(Model 2:OR=1.40,95%CI:1.06-1.86,P=0.02).Subgro-up analyses revealed stronger associations among females,non-smokers,non-drinkers,and less-educated participants.Geographic str-atification showed significant associations in southern but not northern regions.
CONCLUSIONS Solid fuel use,particularly coal for heating,is associated with increased new-onset HD risk.Reducing solid fuel expos-ure is crucial for HD prevention in low-resource settings.
机标关键词：solidheartstudychi-nesecohortdiseasefuelmiddle-aged
论文发表日期：2026-02-28
在线出版日期：2026-03-31（本平台首次上网日期，不代表文献的发表时间）
页数：13( 100-112 )