Associations of diet with infectious diseases in UK Biobank
Junlan Tu1
Xuehong Cai1
Yifan Wang2
Xiangyu Ye1
Meijie Yu1
Sheng Yang3
Rongbin Yu1
Peng Huang1
1.Department of Epidemiology,Center for Global Health,School of Public Health,National Vaccine Innovation Platform,Nanjing Medical University,Nanjing,Jiangsu 211166,China2.Department of Infectious Disease,Jurong Hospital Affiliated to Jiangsu University,Jurong,Jiangsu 212400,China3.Department of Biostatistics,Center for Global Health,School of Public Health,National Vaccine Innovation Platform,Nanjing Medical University,Nanjing,Jiangsu 211166,China
摘要：The current study used multivariable logistic regression analysis to investigate associations between the intake frequencies of 13 food groups(or four diet groups)and infectious diseases.The analysis included 487 849 participants from the UK Biobank,with 75 209 participants diagnosed with infectious diseases.Participants reporting the highest intake frequency of processed meat(odds ratio[OR]=1.096 4,95%confidence interval[CI]:1.062 2-1.131 8)and red meat(OR=1.089 5,95%CI:1.056 3-1.123 9)had a higher risk of infectious diseases,compared with those with the lowest intake frequency.Consuming fish 2.0-2.9 times(OR=0.822 1,95%CI:0.795 5-0.849 6),cheese≥5.0 times(OR=0.882 2,95%CI:0.855 9-0.909 2),fruit 3.0-3.9 servings(OR=0.886 7,95%CI:0.866 1-0.907 8),and vegetables 2.0-2.9 servings(OR=0.937 2,95%CI:0.918 9-0.955 9)per week were associated with a lower risk of infection.Low meat-eaters(OR=0.940 4,95%CI:0.924 3-0.956 7),fish-eaters(OR=0.839 1,95%CI:0.788 7-0.891 9),and vegetarians(OR=0.915 4,95%CI:0.856 1-0.977 8)had a lower risk of infectious diseases,compared with regular meat-eaters.The mediation analysis revealed that glycosylated hemoglobin,white blood cell count,and body mass index served as the mediators in the associations between diet and infectious diseases.The current study indicates that the intake frequency of food groups is a risk factor for infectious diseases,and fish-eaters have a lower risk of infection.
机标关键词：biobankwithassociationsdietdiseasesinfectious
分类号：R155.3(营养卫生、食品卫生)
论文发表日期：2024-11-30
在线出版日期：2026-03-31（本平台首次上网日期，不代表文献的发表时间）
页数：17( 中插7,597-612 )
英文信息