Crocus sativus(Saffron):A potential multifunctional therapeutic agent for neurodegenerative disorders
Yours Sincerely
Mohammad Reza Khazdair
Pharmaceutical Science and Clinical Physiology,Cardiovascular Diseases Research Center,Birjand University of Medical Sciences,Birjand,South Khorasan 9717853111,Iran
摘要：Dear Editor,
Neurodegenerative disorders (NDDs) are age-related disorders characterized by the deposition of abnormal forms of proteins or the progressive loss of neurons in the brain. NDDs are classified according to their pathophysiological properties,including cognitive dysfunction,Alzheimer's disease (AD) and other dementias,Parkinson's disease,and motor neuron disease. The increased oxidative stress and neuro-inflammatory events contribute to neuronal atrophy and death in NDDs[1]. Nitric oxide in the central nervous system has several functions,including the regulation of synaptic plasticity and neurosecretion. The physiological amount of nitric oxide is neuroprotective,whereas higher doses are noticeably neurotoxic[2].
机标关键词：neurodagentcrocusdegenerativedisordersmultifunctionalpotentialsaffron
分类号：R741(神经病学)
论文发表日期：2025-01-30
在线出版日期：2026-03-31（本平台首次上网日期，不代表文献的发表时间）
页数：4( 中插9,114-116 )