Efficacy and safety of EUS-guided coil embolization in combination with cyanoacrylate injection versus conventional endoscopic cyanoacrylate injection in the treatment of gastric varices with spontaneous portosystemic shunts
Dawei Chen1
Sunya Fu2
Ruiwei Shen1
1.Department of Gastroenterology,Ningbo Medical Center Lihuili Hospital,Ningbo,Zhejiang,P.R.China2.Department of Radiology,Ningbo Medical Center Lihuili Hospital,Ningbo,Zhejiang,P.R.China
摘要：Background:Gastric varices(GV)with spontaneous portosystemic shunts(SPSS)pose considerable risks and challenges for adminis-tering endoscopic cyanoacrylate(CYA)injection.This study aimed to evaluate the efficacy and safety of EUS-guided coil embolization in combination with CYA injection compared to conventional endoscopic CYA injection for managing GV with SPSS.
Methods:This retrospective analysis included patients with SPSS treated with either EUS-guided coil embolization in combination with CYA injection or conventional CYA injection for gastric variceal bleeding at Ningbo Medical Center Lihuili Hospital(Zhejiang,China)between January 2018 and March 2023.Patient demographics,procedural details,and follow-up results were reviewed.
Results:The study evaluated 57 patients:21 in the combined treatment group undergoing EUS-guided coil embolization in combina-tion with CYA injection and 36 in the conventional group receiving conventional endoscopic CYA injection.Both cohorts achieved a 100%technical success rate.The mean volume of CYA used was significantly lower in the combined group(1.64±0.67 mL)than in the conventional group(2.38±0.72 mL;P<0.001).Early GV rebleeding rates did not differ significantly between the groups;in contrast,the combined treatment group exhibited a considerably lower incidence of late GV rebleeding than the conventional group(4.8%vs 27.8%,P=0.041).
Conclusions:EUS-guided coil embolization in combination with CYA injection demonstrated superiority over conventional endo-scopic CYA injection in reducing late GV rebleeding in treating GV with SPSS.
机标关键词：injectionsafetycoilwithcombinationconventionalcyanoacrylateefficacy
论文发表日期：2024-04-30
在线出版日期：2026-07-17（本平台首次上网日期，不代表文献的发表时间）
页数：7( 143-149 )
英文信息