Horizontal duodenal papilla is associated with a special spectrum of pancreaticobiliary diseases:a retrospective magnetic resonance cholangiopancreatography-based study
Tiantian Zhang1
Xin Shi2
Jing Li3
Jingsong Zhang4
Xixian Li1
Gui Ren3
Hui Luo3
Xiaoyu Kang3
Shuhui Liang3
Xiangping Wang3
Yanglin Pan3
1.State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases,Xijing Hospital of Digestive Diseases,Fourth Military Medical University,Xi’an,Shaanxi,P.R.China;Department of Gastroenterology,Xi’an Medical University,Xi’an,Shaanxi,P.R.China2.State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases,Xijing Hospital of Digestive Diseases,Fourth Military Medical University,Xi’an,Shaanxi,P.R.China;Department of Pathology,Lanzhou Petrified Total Hospital,Lanzhou,Gansu,P.R.China3.State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases,Xijing Hospital of Digestive Diseases,Fourth Military Medical University,Xi’an,Shaanxi,P.R.China4.Department of Radiology,Xijing Hospital,Fourth Military Medical University,Xi’an,Shaanxi,P.R.China
摘要：Background:Horizontal duodenal papilla(HDP)is not an uncommon ectopic major papilla.The impact of HDP on the occurrence of pancreaticobiliary diseases remains unclear.Here,we explored the associations in patients who underwent magnetic resonance cholangiopancreatography(MRCP).
Methods:Consecutive patients who underwent MRCP at Xijing Hospital(Xi’an,China)between January 2020 and December 2021 were eligible.Patients were divided into HDP and regular papilla(RP)according to the position of the major papilla.The primary out-come was the proportion of congenital pancreaticobiliary diseases.
Results:A total of 2,194 patients were included,of whom 72(3.3%)had HDP.Compared with the RP group(n=2,122),the HDP group had a higher proportion of congenital pancreaticobiliary diseases,especially choledochal cyst(CC)or anomalous pancreaticobiliary junction(APBJ)(6.9%vs 1.4%,P=0.001).More gallbladder cancer(6.9%vs 1.2%,P<0.001)and pancreatic cysts(27.8%vs 16.3%,P=0.01)were also identified in the HDP group.Morphologically,the HDP group had a longer extrahepatic bile duct(8.4[7.6-9.3]cm vs 7.2[6.5-8.1]cm,P<0.001),and larger angles between the common bile duct-duodenum and pancreatic duct-duodenum.Multivariate analysis showed that the presence of HDP was an independent risk factor for gallbladder cancer.
Conclusions:This study confirmed that HDP was not rare in patients underwent MRCP.A higher prevalence of congenital pancreati-cobiliary malformations(especially CC or APBJ),gallbladder cancer and pancreatic cysts was observed in patients with HDP,as well as distinctive morphologic features.
机标关键词：spectrumgraphstudygiopicobcobicholiopa
论文发表日期：2024-08-30
在线出版日期：2026-07-17（本平台首次上网日期，不代表文献的发表时间）
页数：8( 343-350 )
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