DOI: 10.1515/mr-2021-0008
"Know Diabetes by Heart":role of adipocyte-cardiomyocyte communications
Yajing Wang1
Wayne Bond Lau1
Xinliang Ma2
1.Department of Emergency Medicine,Thomas Jefferson University,Philadelphia 19107,PA,USA2.Department of Emergency Medicine,Thomas Jefferson University,1025 Walnut Street,College Building 300,Philadelphia 19107,PA,USA
摘要：Cardiovascular disease is the leading cause of morbidity in patients with diabetes mellitus.In 2019,the American Heart Association and the American Diabetes Association(along with industry leaders)launched the groundbreaking collaborative initiative"Know Diabetes by Heart?"to reduce cardiovascular deaths in type 2 diabetic patients.The molecular basis linking diabetes with car-diovascular complications has not yet been fully defined.Recent clinical and experimental studies strongly suggest that adipocyte dysfunction and subsequent pathological communications between adipocyte and cardiomyocytes play important roles in diabetic cardiac injury.This perspective article will review recent development con-cerning adipocyte-cardiomyocyte communications,and identify the most critical questions remain to be answered in this filed.
机标关键词：heartroleadipocytecardiomyocytecommunicationsdiabetesknow
论文发表日期：2021-02-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 14-17 )
英文信息