DOI: 10.1515/mr-2022-0002
Adiponectin:friend or foe in obesity and inflammation
Liping Luo1
Meilian Liu2
1.Department of Biochemistry and Molecular Biology,University of New Mexico Health Sciences Center,Albuquerque,NM 87131,USA;Department of Endocrinology,Endocrinology Research Center,Xiangya Hospital,Central South University,Changsha,Hunan Province 410008,China2.Department of Biochemistry and Molecular Biology,University of New Mexico Health Sciences Center,Albuquerque,NM 87131,USA
摘要：Adiponectin is an adipokine predominantly produced by fat cells,circulates and exerts insulin-sensitizing,cardioprotective and anti-inflammatory ef-fects.Dysregulation of adiponectin and/or adiponectin signaling is implicated in a number of metabolic diseases such as obesity,insulin resistance,diabetes,and cardio-vascular diseases.However,while the insulin-sensitizing and cardioprotective effects of adiponectin have been widely appreciated in the field,the obesogenic and anti-inflammatory effects of adiponectin are still of much debate.Understanding the physiological function of adi-ponectin is critical for adiponectin-based therapeutics for the treatment of metabolic diseases.
机标关键词：adiponectinfriendinflammationobesity
论文发表日期：2022-08-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：14( 349-362 )
英文信息