Current state of stem cell research in non-human primates:an overview
Junmo Wu1
Yuxi Shi1
Shanshan Yang1
Zengli Tang1
Zifan Li1
Zhuoyao Li1
Jiawei Zuo1
Weizhi Ji2
Yuyu Niu2
1.Kunming University of Science and Technology,Kunming,Yunnan Province,China;Yunnan Key Laboratory of Primate Biomedical Research,Kunming,Yunnan Province,China2.State Key Laboratory of Primate Biomedical Research;Institute of Primate Translational Medicine,Kunming University of Science and Technology,Kunming 650500,Yunnan Province,China;Yunnan Key Laboratory of Primate Biomedical Research,Kunming 650500,Yunnan Province,China
摘要:The remarkable similarity between non-human primates(NHPs)and humans establishes them as essential models for understanding human biology and diseases,as well as for developing novel therapeutic strategies,thereby providing more comprehensive reference data for clinical treatment.Pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells provide unprece-dented opportunities for cell therapies against intractable diseases and injuries.As continue to harness the potential of these biotechnological therapies,NHPs are increasingly be-ing employed in preclinical trials,serving as a pivotal tool to evaluate the safety and efficacy of these interventions.Here,we review the recent advancements in the fundamental research of stem cells and the progress made in studies involving NHPs.
机标关键词:overviewresearchcurrentstemstatecellnon-humanprimates
论文发表日期:2023-08-28
在线出版日期:2025-08-15(本平台首次上网日期,不代表文献的发表时间)
页数:28( 277-304 )
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年,卷(期):2023,3(4)
所属栏目:Reviews