DOI: 10.1515/mr-2023-0029
Iron oxide nanoparticles in magnetic drug targeting and ferroptosis-based cancer therapy
Quazi T.H.Shubhra
Department of Neurosurgery,Renmin Hospital of Wuhan University,Wuhan 430060,Hubei Province,China;Institute of Chemistry,University of Silesia in Katowice,41-500 Chorzów,Poland
摘要：Iron oxide(IO)nanoparticles(NPs)have gained significant attention in the field of biomedicine,particularly in drug targeting and cancer therapy.Their potential in magnetic drug targeting(MDT)and ferroptosis-based cancer therapy is highly promising.IO NPs serve as an effective drug delivery system(DDS),utilizing external magnetic fields(EMFs)to target cancer cells while minimizing damage to healthy organs.Additionally,IO NPs can generate reactive oxygen species(ROS)and induce ferroptosis,resulting in cytotoxic effects on cancer cells.This article explores how IO NPs can potentially revolutionize cancer research,focusing on their applications in MDT and ferroptosis-based therapy.
机标关键词：ferroptosiscanceroxidebaseddrugironmagneticnanoparticles
论文发表日期：2023-10-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：4( 444-447 )
英文信息