DOI: 10.1515/mr-2024-0036
Redefining chronic mountain sickness:insights from high-altitude research and clinical experience
Gustavo Zubieta-Calleja
Pulmonary,High Altitude Pulmonary and Pathology Institute(HAPPI-IPPA),Av.Copacabana-Prolongación # 55,La Paz,Bolivia
摘要：Chronic Mountain Sickness(CMS),characterized by increased red blood cells above average values traditionally attributed to chronic hypobaric hypoxia exposure,is being redefined in light of recent research and clinical experience.We propose a shift in perspective,viewing CMS not as a singular entity but as Poly-erythrocythemia(PEH),as the Hematocrit/Hemoglobin/Red Blood Cells(Ht/Hb/RBCs)increase constitutes a sign,not a disease reflecting a spectrum of oxygen transport alterations in multiple diseases in the chronic hypoxia envi-ronment in high-altitude populations.Drawing on over five decades of experience at the High Altitude Pulmonary and Pa-thology Institute(HAPPI-IPPA)in Bolivia,we advocate for altitude-specific blood parameter norms and emphasize the importance of correct etiological diagnosis for effective man-agement.This updated understanding not only aids in managing chronically hypoxemic patients at various altitudes but also of-fers valuable insights into global health challenges,including the recovery from COVID-19.
机标关键词：insightsresearchclinicalfromchronicexperiencehigh-altitudemountain
论文发表日期：2025-02-28
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：22( 44-65 )
英文信息