生物3D打印支架在骨缺损修复中的研究进展
范宗泽1
孙吉宁1
李忠海2
1.116600 辽宁省,大连理工大学机械工程学院2.116600 辽宁省,大连医科大学附属第一医院骨科
摘要：3D bioprinting technology has emerged as a revolutionary breakthrough in tissue engineering,providing innovative solutions for bone defect repair.In recent years,significant advancements have been made in the application of 3D bioprinted scaffolds for bone tissue engineering.This article systematically reviews the current research status and development trends of this technology in bone defect repair.Regarding materials,hydrogel and bioceramic composite systems demonstrate excellent biocompatibility and osteoinductive properties.In terms of printing techniques,continuous innovations in inkjet printing and stereolithography have enabled precise control over scaffold microstructures.As for scaffold design,novel concepts such as hierarchical porosity and biomimetic gradient structures have significantly improved both mechanical properties and biological functionality.Currently,several 3D-printed bone repair products have entered clinical applications,demonstrating promising therapeutic outcomes in treating bone tumors,infections,and traumatic injuries.Looking ahead,with deeper interdisciplinary integration,3D bioprinted scaffolds are expected to provide optimized solutions for personalized bone defect repair.
关键词：打印三维组织支架骨再生综述
分类号：R687.3(骨科学（运动系疾病、矫形外科学）)
论文发表日期：2025-12-19
在线出版日期：2026-01-05（本平台首次上网日期，不代表文献的发表时间）
页数：7( 1146-1152 )
英文信息