Neuronal swelling implicated in functional recovery after spinal cord injury
Qiang Li
Department of Neurobiology,University of Texas Medical Branch,Galveston,TX,USA;Department of Neurosurgery,Massachusetts General Hospital,Harvard Medical School,Boston,MA,USA
摘要：Spinal cord injury(SCI)often results in permanent dysfunction of locomotion,sensation,and autonomic regulation,imposing a substantial burden on both individuals and society(Anjum et al.,2020).SCI has a complex pathophysiology:an initial primary injury(mechanical trauma,axonal disruption,and hemorrhage)is followed by a progressive secondary injury cascade that involves ischemia,neuronal loss,and inflammation.Given the challenges in achieving regeneration of the injured spinal cord,neuroprotection has been at the forefront of clinical research.Yet,current neuroprotective therapeutic efficiency is limited(Anjum et al.,2020).To develop effective neuroprotective interventions for SCI patients,a deeper understanding of SCI pathophysiology is undoubtedly required.
机标关键词：recoveryaftercordfunctionalimplicatedinjuryneuronalspinal
论文发表日期：2026-04-30
在线出版日期：2026-03-25（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1558-1559 )