Imaging alpha-synuclein pathology in Parkinson's disease
Ruiqing Ni
Institute for Regenerative Medicine,University of Zurich;Institute for Biomedical Engineering,ETH Zurich and University of Zurich,Zurich,Switzerland;Department of Nuclear Medicine,Inselspital,Bern University Hospital,University of Bern,Bern,Switzerland
摘要：Parkinson's disease(PD)is the second most common neurodegenerative disorder.The clinical manifestations of PD include motor symptoms,such as bradykinesia,resting tremor,rigidity,and nonmotor symptoms,which include disturbances in sleep,gastrointestinal function,and olfaction.PD misdiagnosis rates have been reported to reach approximately 30％,partly owing to the heterogeneity of parkinsonism with non-PD pathologies,and the differential diagnosis of PD from neurodegenerative diseases such as multiple systemic atrophy(MSA)and progressive supranuclear palsy poses another unmet need.
机标关键词：parkinsonimagingalpha-synucleindiseasepathology
论文发表日期：2026-04-30
在线出版日期：2026-03-25（本平台首次上网日期，不代表文献的发表时间）
页数：2( 1566-1567 )