The Effects of Cyclic Stretching on the Proliferation of Lung Adenocarcinoma Cells in Vitro
QU Hua
WU Wen-zhou
CHEN Wei-yi
摘要：Using FX-4000 strain unit, the prolieration in human lung adenocarcinoma A549 cells that underwent mechanical strain of different waveform、frequency and duration were studied. Image analysis revealed that cellular proliferation rate(PR) reduced significantly after cells were subjected to square wave with 0～20% elongation at frequency 30,40,50 and 60 cycles/min for 2h. The PR had no distinct difference at heart wave , triangle wave and sine wave group compared with control. It is concluded that square wave and higher frequency play an important role in inhibiting A549 cells proliferation.
机标关键词：
分类号：R3(基础医学)
资助基金：国家自然科学基金(10332060)山西省自然科学基金(20041002)
论文发表日期：2006-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：5( 31-35 )
英文信息