Preparation of Aminated Macroporous Polyvinyl Alcohol Resins and Evaluation for Bilirubin Adsorption
WANG Wei-chao
ZHANG Sheng-nan
HU Yue-han
XIE Hui
OU Lai-liang
YU Yao-ting
KONG De-ling
GU Han-qing
摘要：In the present study we prepared macroporous polyvinyl alcohol beads. A series of bilirubin adsorbents were generated by immobilization of eight amine agents to the beads as ligands. The adsorption of bilirubin was evaluated by in vitro static and dynamic adsorption tests. The results show that these adsorbents have excellent adsorption efficiency and capacity. Among the eight ligands, trimethylamine (TMA), triethylamine (TEA) and 1,6- hexanediamine(HAD) showed the highest adsorption capacity. The adsorption equilibrium can be achieved in half an hour, and the adsorption percentage of bilirubin was up to 80%. Static electricity and hydrophobic interaction played the main role in bilirubin adsorption, and the adsorption was found to match the monolayer model. The excellent adsorption of these adsorbents indicates their potential in clinical treatment.
机标关键词：hydrophobic interactionadsorption equilibriumadsorption efficiencyadsorption capacitydynamic adsorptionclinical treatmentpolyvinyl alcoholin vitro
分类号：R318.08(医用一般科学)
论文发表日期：2008-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：8( 93-100 )
英文信息