The Influence of RNA Secondary Structure on the Efficiency of siRNA Silencing
SUN Ying
GUI Jian-bin
CHEN Zhao-xue
摘要： In the application of RNAi technology, it is an essential step to design siRNA applicable to target gene. At present, there are many researches and conclusions on siRNA design. This paper aims to the influences of mRNA secondary structure or siRNA antisense-strand secondary structure on siRNA silence efficiency. The paper also discusses the problems and sets out further insights in the research.
机标关键词：secondary structuretarget gene
分类号：R318.04(医用一般科学)
论文发表日期：2015-01-01
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：6( 179-184 )
英文信息