Comparative Analysis of the Effect of Local Citrate Anticoagulation and Non-anticoagulation in Extended Intermittent Renal Replacement Therapy(PIRRT)
FU Bi-ling
SHEN Xun
LIU Ying-shan
ZHANG Ai-sha
ZHOU Li
CHEN Ji-hong
Department of Nephrology,Shenzhen Bao'an District People's Hospital,Shenzhen Guangdong 518101,China
摘要：Objective:To observe the anticoagulant effect of local citrate anticoagulation and non-anticoagulation in prolonged intermittent renal replacement therapy(PITTR).Methods:From October 2018 to October 2019,30 patients with a high risk of bleeding who received PIRRT treatment in our hospital were selected and divided into RCA group(citrate group)and control group(non-anticoagulant group),15 cases in each group.The anticoagulant efficiency,filter service life,coagulation function,and blood gas indexes were compared between the two groups.Results:(1)the anticoagulant effective rate of the RCA group was higher than that of the control group,and the use time of the filter was longer than that of the control group(P＜0.05).(2)There was no significant difference in Pt and APTT between the two groups before and after treatment(P＞0.05).(3)There was no significant difference in plasma calcium concentration between the two groups before treatment,4,6 and 8 h after treatment(P＞0.05).(4)In the RCA group,the pH value and be valued at 4,6 and 8 h after treatment were higher than those before treatment,but they were in the normal range,and the difference was statistically significant(P＜0.05).Conclusion:In the extended intermittent renal replacement therapy,the effect of local citrate anticoagulation is better than that of non-anticoagulant therapy,which can prolong the service life of the filter,and there are no adverse reactions such as prolonged coagulation time,hypocalcemia,and metabolic acid-base imbalance.
机标关键词：
分类号：R459.5(治疗学)
论文发表日期：2021-03-30
在线出版日期：2025-08-15（本平台首次上网日期，不代表文献的发表时间）
页数：7( 13-19 )
英文信息