The cardiovascular aspects of a Ménière's disease population-A pilot study

Angela Reis Rego; David Dias; Ana Pinto; Sandra Sousa e Castro; Telma Feliciano; Cecília Almeida e Sousa

doi:10.3760/j.issn.1672-2930.2019.02.003

摘要：Introduction:MD is considered a rare disease.An adequate model that explains MD's pathophysiology is not well established.Recently,the vascular theory of the disease has been revived.Objectives:To characterize a MD population according to its cardiovascular risk and correlate it to the MD clinical course.Methods:In this retrospective chart study the data of 31 MD patients observed between January 2017 and April 2018 in a tertiary university hospital were reviewed.Patients included in the study were diagnosed according to the Bárány Society criteria.Lost follow-ups,patients with autoimmune disease,atopy or allergy,major psychiatric disease and migraine were excluded.Age,gender,cardiovascular risk factors,audiometric and vestibular parameters,occurrence of MD attacks in the previous 6 months,vestibular medication in course and time course of MD were recorded and compared between groups (with and without cardiovascular risk factors).Results:31 patients (61.3％ females) mean aged 60.3 years (±9.7) were studied.74％ of the population had at least one risk factor and 51.6％ of patients had attacks in the last 6 months.There was a statistically significant difference in the occurrence of MD attacks in the last 6 months (p =0.014) between MD patients with and without risk factors.Mean PTA thresholds were higher and speech discrimination was lower in individuals with more cardiovascular risk factors.Conclusions:Treatment of MD focusing on vascular risk factors may allow a better control of symptoms and result in a decreased need for ablative procedures in this disorder.