Otolith Degeneration with Aging:Insights from Video Ocular Counter-Roll(vOCR)Assessment
Melissa Castillo-Bustamante1
Jorge Madrigal2
Elizabeth Andalón-Dueñas3
Johanna Marcela Vanegas4
Ireri Espinoza5
1.School of Health Sciences,Universidad Pontificia Bolivariana,Street 1(a)70-01,Medellín,Colombia;Clínica Universitaria Bolivariana,Street 78A # 72B-109,Medellín,Colombia2.Facultad Mexicana de Medicina,Universidad La Salle México.Ciudad de México,México3.Centro de Vértigo y Mareo.Guadalajara,México4.School of Health Sciences,Universidad Pontificia Bolivariana,Street 1(a)70-01,Medellín,Colombia5.Centro de Vértigo y Mareo.Ciudad de México,México
摘要：Background:Vestibular assessments,such as the video ocular counter roll(vOCR)test,offer valuable insights into the interactions between age,otolith function,and vestibular performance.Objective:To analyze the relation between age and vOCR gains as a potential marker of age-related otolith degeneration.Methods:A total of 107 participants underwent vOCR testing.Descriptive statistics and simple linear regression analyses were conducted to explore the association between age and vOCR gains.Results were presented using regression coefficients,95％confidence intervals,p-values,and R-squared values.Results:In the overall sample,statistically significant associations were observed between age and vOCR gains in both ears.For the right ear,vOCR gains decreased with increasing age(coefficient:-0.03;95％CI:-0.05 to-0.01;p＜0.001;R2=0.08),while the left ear showed a slightly stronger association(coefficient:-0.04;95％CI:-0.07 to-0.02;p＜0.001;R2=0.12).These findings indicate a moderate age-related decline in otolith-mediated vestibular responses.Conclusion:vOCR gains appear to decline with age,reflecting potential age-related otolith degeneration.These results support the clinical value of vOCR as a non-invasive method to assess vestibular function and its changes across the lifespan.
机标关键词：insightsvideowithfromagingassessmentcounter-rolldegeneration
论文发表日期：2025-07-30
在线出版日期：2025-11-07（本平台首次上网日期，不代表文献的发表时间）
页数：6( 198-203 )
英文信息