1Animal models and experimental medicine and the Nobel Prize in Physiology or Medicine 2021— TRPV and PIEZO receptors for temperature and touch sensationYu Zhang，Dongyuan Zhang，Chuan QinResearch Highlights296-299
2Hypoxia adaptation in the cornea: Current animal models and underlying mechanismsKunpeng Pang，Anton Lennikov，Menglu YangSpecial Section Reviews300-310
3Adaptation of mammals to hypoxiaFang Li，Zhenglei Qiao，Qijiao Duan，Eviatar NevoSpecial Section Reviews311-318
4The hypoxia adaptation of small mammals to plateau and underground burrow conditionsMengke Li，Dan Pan，Hong Sun，Lei Zhang，Han Cheng，Tian Shao，Zhenlong WangSpecial Section Reviews319-328
6A novel mind- set in primate experimentation: Implications for primate welfareAntonella Tramacere，Atsushi IrikiReviews343-350
7Establishment of an oligoasthenospermia mouse model based on TAp73 gene suppressionHong-Juan Liu，Meng-Yun Deng，Yan-Yan Zhu，De-Ling Wu，Xiao-Hui Tong，Li Li，Lei Wang，Fei Xu，Tong-Sheng WangOriginal Articles351-358
8Development of a unilateral ureteral obstruction model in cynomolgus monkeysLinghong Huang，Jia Ni，Tanika Duncan，Zhizhan Song，Timothy S.JohnsonOriginal Articles359-368
9Implication of proliferation gene biomarkers in pulmonary hypertensionYi Yan，Rong Jiang，Ping Yuan，Li Wen，Xiao-Bin Pang，Zhi-Cheng Jing，Yang-Yang He，Zhi-Yan HanOriginal Articles369-380
10Novel rat model of multiple mitochondrial dysfunction syndromes (MMDS) complicated with cardiomyopathyYahao Ling，Jiaxin Ma，Xiaolong Qi，Xu Zhang，Qi Kong，Feifei Guan，Wei Dong，Wei Chen，Shan Gao，Xiang Gao，Shuo Pan，Yuanwu Ma，Dan Lu，Lianfeng ZhangOriginal Articles381-390
11Closed cranial window rodent model for investigating hemodynamic response to elevated intracranial pressureMatt T.Oberdier，James F.Antaki，Alexander Kharlamov，Stephen C.JonesOriginal Articles391-397
12Safety and biodegradability of a synthetic dural sealant patch (Liqoseal) in a porcine cranial modelAhmet Kinaci，Wilhelmina Bergmann，Sander van Thoor，Saskia Redegeld，Albert van der Zwan，Tristan P.C.van DoormaalOriginal Articles398-405
13In- depth examination of hyperproliferative healing in two breeds of Sus scrofa domesticus commonly used for researchColton H.Funkhouser，Liam D.Kirkpatrick，Robert D.Smith，Lauren T.Moffatt，Jeffrey W.Shupp，Bonnie C.CarneyOriginal Articles406-417
14Heterozygous lipoprotein lipase knockout mice exhibit impaired hematopoietic stem/progenitor cell compartmentGuiying Shi，Xinyue Li，Keya Li，Yiying Huang，Xuepei Lei，Lin Bai，Chuan QinOriginal Articles418-425
