1Building an international platform for the research,development,and dissemination of new knowledge in the field of laboratory animal science,technology,and experimental medicineMuhammad Iqbal ChoudharyEditorial4
2Improving dexamethasone drug loading and efficacy in treating rheumatoid arthritis via liposome:Focusing on inflammation and molecular mechanismsMohammad Yasin Zamanian，Hamidreza Zafari，Maria K.Osminina，Alla A.Skakodub，Raed Fanoukh Aboqader Al-Aouadi，Maryam Golmohammadi，Nikta Nikbakht，Iman FatemiThemed Section:Review5-19
3Unwanted disorders and xenogeneic graft-versus-host disease in experimental immunodeficient mice:How to evaluate and how to reportSeyed Mostafa Monzavi，Samad Muhammadnejad，Vahid Mansouri，Hami Ashraf，Naser AhmadbeigiThemed Section:Review20-29
4Single-cell sequencing reveals the features of adaptive immune responses in the liver of a mouse model of dengue feverYizhen Yuan，Qian Chen，Zhe Li，Fangzhou Cai，Dan Li，Wei WangThemed Section:Original Article30-43
5Emodin promotes the recovery of rheumatoid arthritis by regulating the crosstalk between macrophage subsets and synovial fibroblast subsetsLianying Cheng，Xiaofeng RongThemed Section:Original Article44-56
6The transcriptome of MHV-infected RAW264.7 cells offers an alternative model for macrophage innate immunity researchYun Liu，Ting-Ting Feng，Wei Tong，Zhi Guo，Xia Li，Qi Kong，Zhi-Guang XiangThemed Section:Short Communication57-66
7Isoproterenol mechanisms in inducing myocardial fibrosis and its application as an experimental model for the evaluation of therapeutic potential of phytochemicals and pharmaceuticalsLujain Bader Eddin，Mohamed Fizur Nagoor Meeran，Niraj Kumar Jha，Samer N.Goyal，Shreesh OjhaReview67-91
8Rat models of frozen shoulder:Classification and evaluationHezirui Gu，Wenqing Xie，Hengzhen Li，Shuguang Liu，Yusheng LiReview92-101
9Targeting ASK1 by CS17919 alleviates kidney-and liver-related diseases in murine modelsGuoqiang Liao，Qianjiao Yang，Xuhua Mao，Yiru Zhao，Beizhong Chen，Kun Zhang，Yu Zhang，Ping Zhang，Zhengli Chen，Shengjian HuangOriginal Article102-113
10The N-terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolismXue Wang，Chunyou Ning，Xingyi Cheng，Zhengzhong Wu，Dongbo Wu，Xuemei Ding，Cunxiang Ju，Zhihang Zhou，Lingfeng Wan，Wei Zhao，Peiliang ShiOriginal Article114-125
11The collaborative cross mouse for studying the effect of host genetic background on memory impairments due to obesity and diabetesAvia Paz，Kareem Midlej，Osayd Zohud，Iqbal M.Lone，Fuad A.IraqiOriginal Article126-141
12Dyssynchronous heart failure models in canines:New insights into electrocardiographic,echocardiographic and histological featuresHan Jin，Shengwen Yang，Hao Huang，Sijing Cheng，Pengkang He，Sixian Weng，Min Gu，Hongxia Niu，Wei Hua，Yiran Hu，Hui LiOriginal Article142-153
13Causal relationship between lipid profile and muscle atrophy:A bi-directional Mendelian randomization studyKun Chen，Peng Gao，Xiaoxiang Fang，Kexing Tang，Pan Ouyang，Zongchao Li，Liangjun Li，Zhenhan DengOriginal Article154-161
14High expression of SULF1 is associated with adverse prognosis in breast cancer brain metastasisYitong Li，Tingting Feng，Qinghong Wang，Yue Wu，Jue Wang，Wenlong Zhang，Qi KongOriginal Article162-170
15dP/dtmax:An underestimated prognostic factor in large animal infarction modelRita Garamvölgyi，Dénes Kőrösi，Ottó Tátrai，Emőke Bodor，Dániel Fajtai，Kornélia Farkas，András VorobcsukShort Communication171-178
16Evaluation of a user-friendly CSDS cage apparatus for studying depressive-like behaviors in rodentsHao Zhang，Dongmei Gao，Minghu Hu，Wanqing Zhou，Muxuan Han，Ya Sun，Yang Zhang，Jieqiong Wang，Mingzhou GaoShort Communication179-186
17Generation of transgenic chicken through ovarian injectionJinghua Jiang，Caiying Wang，Xuguang Du，Fei Gao，Sen WuShort Communication187-193
